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MANHATTAN, NEW YORK
Perfect for: Anyone looking for great food, endless drinks, and millions of singles to share them with
The scene: It's easy to forget that Manhattan is an island, too, at least until you have to take a traffic-clogged bridge or tunnel to get there. New York City (view slideshow) is special because of all the striving, hot young singles who have left their own uncool towns to make it here. The upshot, even if you're just visiting Manhattan, is the chance to eat, drink, dance, and potentially hook up with them in a relatively confined space. (Despite their reputation, New Yorkers are very easy to chat up in a bar—just don't try it on the street or subway.) As for where to see those fast-walking studs and beauties, well, they're everywhere. Take a stroll in Union Square, in Nolita, along Fifth Avenue. Then follow the best-looking ones into that restaurant/pub/gallery/boutique they're headed into.
Don't miss: Happy hour, which runs from the time when everyone empties out of their offices and goes out for "just one drink" until 4 am. For a good look at the latest/greatest spots, see our updated New York nightlife guide. The sexiest bars are those behind Manhattan's cocktail renaissance, with hand-chipped ice, fresh-squeezed mixers, and innovative concoctions. At places like Death & Co. and the Pegu Club, the drinks are good, but the eclectic, smart, and hot-looking clientele is even better.
Between the sheets: Midtown is not so sexy, Wall Street less so (especially these days). You want to hang where the actors, artists, models, and other beautiful people actually live. So book a night at Robert De Niro's new Greenwich Hotel in Tribeca. It's warm and friendly, with decent-size rooms, and the bar and restaurant, Ago, is hopping with hotties, even if the food's only so-so.