Hypoallergenic Rooms, Four Seasons Hotel Chicago, Chicago

With bed bug fears at an all-time high, the immaculate Four Seasons Chicago has a convenient response to the zeitgeist of paranoia: three hypoallergenic guest rooms that are so pristine that even Howard Hughes could've made himself at home here. These decidedly deluxe rooms (including one suite) have hardwood floors instead of carpets, shades but no curtains, and hypoallergenic bedding and toiletries. Plus, the housekeeping staff wouldn't dream of using anything but allergen-free solutions as they're scrubbing away the tiniest specks of dust. Of course, the hotel's 342 other rooms, minimal in crisp white-and-blue decor, are also clean as a whistle. And the hotel's location, on floors 31 through 46 of a limestone North Michigan Avenue tower with stunning views of the lake or the Chicago skyline, will make you feel safe and above the fray no matter which room you book.

Four Seasons Hotel Chicago
Chicago, Illinois
Tel: 312 280 8800
Hypoallergenic rooms from $345 per night.

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