The dramatic landscape of Patagonia can feel like the final frontier. And if you want to explore the region, the new Singular Patagonia hotel, near Puerto Natales, Chile, is ready to indulge your intrepid side. Fourth-generation descendants of European settlers to the area spent ten years restoring this 1915 sheep-farming building. The industrial-chic result offers five-star room and board, plus primo expeditions, wrapped in nearly 100 years of history.

Days are spent trekking, condor watching, visiting caves on horseback, kayaking past glaciers, or just relaxing in the spa. Evenings call for red wine, king crab, and Magellan lamb in the brick warehouse turned dining room. The 57 guest rooms beckon in a new wing outfitted with soaking tubs and a distinctly masculine mix of concrete, brass, marble, and polished wood. And the in-bed views out to the Fjord of Last Hope? Well, you'll understand why the owners' ancestors settled here.

Photo: Courtesy of Singular Patagonia