The brainchild of London music producer Tom Rixton and his wife, Patricia O'Shea, this 17-bed hotelthe first in fashionable Palermo Hollywoodis wedged in among ultra-cool bars and fusion eateries. With an exterior bathed by night in hallucinogenic shades of apple green and lemon and a spartan interior warmed by touches of 1960s retro, it's centered around a cocktail bar, a kitchen producing tasty tapas, and a lush garden surrounding a sizable pool. Guests can listen to Rixton's mixes in the hotel's "tune zones" or borrow CDs from its libraryrooms are wired for sound. A fern-bedecked spa in the basement offers treatments to alleviate jet lag, stress, or the inevitable hangover.
When to go: Buenos Aires's buzz never stops.
Which room to book: The Garden Suite offers privacy, a whirlpool with a sky view, and a roof terrace (doubles, $115–$140).
Amenities:
24-hour Room Service,
Bar/lounge,
Pool,
Spa