700 W. Main Street
Tel: 502 217 6300
This 91-room hotel, hung with works from the owner's private collection (including pieces by Andres Serrano and Sam Taylor-Wood), pays homage to twenty-first-century art. Further distinguishing it from Louisville's stately hotels are its 5,000-square foot gallery and witty plastic penguins, which staff rotate around the lobby. Each room comes with the usual gadgets, plus fun extras such as poster art to take home. Proof on Main serves gorgeous cuts of bison and does a snazzy take on country ham fritters.