Address: 3131 Las Vegas Blvd. South
Wynn's latest hot spot is more house party than sprawling nightclub or sticky frat bash. The focal point of the 4,500-square-foot space is the onyx-lit dance floor, which is surrounded by plush banquettes (equipped with lockers for storing personal effects while you bust a move) and is illuminated by 300 color-changing lanterns. Go on industry Tuesdays and house Thursdays, arriving early in your best Jimmy Choos to witness the transformation from mellow lounge to pulsing discotheque. Sip one of the signature muddled fruit concoctions, such as the pineapple- and ginger-infused Caribbean Blush, on the leafy outdoor patio.