Though the Sè is very much a visual feastwith a massive bronze front door, a grand staircase framed by faux sand dollars, lamps covered in gray stingray, an entire wall at the spa covered in tiny green Chinese teacupsit's more than just a pretty face. The staff seem to be genuinely thrilled to help you, and the 184 rooms, in a steel-and-glass building perched atop a Victorian-era structure, are small but well appointed. Yet the thing that really sticks in your mind (and belly) is the complimentary breakfast in bed with chocolate croissants, serrano ham and melon, and granola. All of this from chef Christopher Lee, whose Suite & Tender restaurant is surf and turf with a twist: pork belly and scallops, hamachi fish tacos, carpaccio of Kobe beef. The spa, too, is a pleasant surpriseespecially the harem-style lounge, where you can curl up with a good book (or another warm body).
When to go: The adjacent Gaslamp District rocks year-round.
Which room to book: Suites in the northwest corner (rooms 909, 809, 709, etc.) have balconies overlooking the rooftop pool and downtown San Diego.