Grand Hyatt Cairo, Cairo $$$$
Concierge.com's insider take:
This sleek, white, Y-shaped tower looks out over the Nile from the northern tip of Roda Island—which is picturesquely set in the middle of the river. The 716 rooms and suites take full advantage of the location; almost all have private balconies for enjoying the vistas. Mostly modern in decor, they're spruced up with warm wood and subtly gilded pieces that recall Empire furnishings of the Napoleonic era. The service here is extremely friendly and helpful, and the plethora of dining options—including Italian, French, and tandoori restaurants, a food court, and dinner dances aboard a yacht—is a little overwhelming. If you're after an authentic Egyptian meal, try Nubian Village; for that on-top-of-the-world feeling, head to the Revolving Restaurant, 444 feet up and one of the highest in the Middle East.