see + do
Concierge.com's insider take:
The church of Ognissanti, or All Saints, has a grand Baroque facade that was designed in 1672, but was actually founded in the 13th century by the Umiliati. Sandro Botticelli and Amerigo Vespucci are buried here, and there is some fine art, including frescoes and a St. Jerome by Ghirlandaio, a St. Augustine by Botticelli, and works by Taddeo and Agnolo Gaddi in the sacristy. But the jewel lies in the adjacent refectory of the old convent (open Mon, Tues, and Sat 9 a.m.–noon). Here you'll find one of Domenico Ghirlandaio's most famous works, his fresco of the Last Supper or Cenacolo.
Open 9 a.m. to 2:30 p.m. and 4 p.m. to 7:30 p.m. daily.